Epigenetics Lecture WS 2019
This is my actual presentation on epigenetics.
Encyclopedia of Cancer
The chapter on mevalonate pathway, which I authored together with my colleague Franz Varga has appeared in the recent edition of The Encyclopedia of Cancer (3rd edition, vol.2, Elsevier Academic Press, pp. 445-457). Downloads (see: publications>epigenetic) are allowed for non-commercial research and educational use.
Lecture Epigenetic Conference 2017
Here is the lecture on "Epigenetic aspects of antineoplastic activities from drugs affecting mevalonate metabolism" for the Epigenetics conference in Frankfurt on Nov. 6th, 2017.
Statins and Bisphosphonates against cancer
Our new publication which shows how statins and bisphosphonates induce a process of starvation in fast growing cancer cells has been published in the IJMS (International Journal of Molecular Science).
LBG Health Meeting 2016
LBG14 Poster HKFV LBIO fertig.pdf (3,8 MB)
LBG A Health KOKU Poster.pdf (3,4 MB)
Here are our Posters, which have been presented at the Health Meeting from the Ludwig Boltzmann Society in Vienna on November 28th and 29th 2016.
Interaction of bone and leukemic cells
An article discussing the cose interaction from bone and leukemic cells is published in the journal JATROS.
Leukemia and Bone Cells
This poster was presented at the spring meeting of the Austrian Society for Hematology and Oncology (Mar 17-19, 2016).
Epigenetic effect of Simvastatin in neoplastic mast cells
This poster was presented on the 20th Congress of the European Hematology Association in Vienna (June 11-14, 2015).
Epigenetics of Mevalonate Metabolism
This article provides some insight into the epigenetic mechanisms, which may be responsible for the anti-cancer activities of statins and bisphosphonates
Epigenetics of Mevalonate Metabolism Poster
This poster is presented at the spring meeting of the Austrian Society for Hematology and Oncology (April 24th 2015). It focuses on different effects of statins and bisphosphonates on respective gene expression patterns.
Epigenetics of Vitamin D Metabolism
This poster, which is presented at the Epigenetic control of hematopoiesis and leukemogenesis Symposium in Strasbourg on April 21st 2015, illustrates the epigenetic activity of vitamin D.
Epigenetics and the Power of Art
Here is one of the first publications indicating the connection between epigenetics and artistic performance.
The role of epigenetics in the regulation of apoptosis in myelodysplastic syndromes and acute myeloid leukemia
Publications 2012
Ghanim et al Blood 2012.pdf (2,3 MB)
Stefanska et al 2012.pdf (1,0 MB)
Here are publications from the year 2012 and early 2013
Impact of Vitamin D Metabolism on Clinical Epigenetics
The beneficial effects of vitamin D for prevention and treatment of numerous diseases are well known. This publication gives interesting insights on the molecular background of vitamin D-action.
Epigenetic effect of homocysteine
Our great study demonstrating how the type-2 diabetes - associated metabolite homocysteine may exert its cancerogeneic potential is now published in the "Journal of Biological Chemistry".
Epigenetics and Human Health Book Chapter Text
Effects of Epigenetic Drugs (Vorinostat, Decitabine) on Metabolism- Related Pathway Factors in Leukemic Cells
This article demonstrates the inhibitory effect of epigenetically active drugs on energy metabolism of leukemia cell lines. Suppementary Figures available on request.